Silvia Munoz-Descalzo

Visiting Research Fellow

Start Year


End Year


Current Position:
Research Group Leader and Investigator, University of the Canary Islands, Canary Islands, Spain


Muñoz-Descalzo S, Hadjantonakis AK, Arias AM. (2015) Wnt/ß-catenin signalling and the dynamics of fate decisions in early mouse embryos and embryonic stem (ES) cells. Semin Cell Dev Biol 47-48:101-9. doi: 10.1016/j.semcdb.2015.08.011. Epub 2015 Aug 29. Review. PubMed PMID: 26321498; PubMed Central PMCID: PMC4955857.

Lou X, Kang M, Xenopoulos P, Muñoz-Descalzo S, Hadjantonakis AK. (2014) A rapid and efficient 2D/3D nuclear segmentation method for analysis of early mouse embryo and stem cell image data. Stem Cell Reports 2(3):382-97. doi: 10.1016/j.stemcr.2014.01.010. eCollection 2014 Mar 11. PubMed PMID: 24672759; PubMed Central PMCID: PMC3964288.

Le Bin GC, Muñoz-Descalzo S, Kurowski A, Leitch H, Lou X, Mansfield W, Etienne-Dumeau C, Grabole N, Mulas C, Niwa H, Hadjantonakis AK, Nichols J. (2014) Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development 141(5):1001-10. doi: 10.1242/dev.096875. Epub 2014 Feb 6. PubMed PMID: 24504341; PubMed Central PMCID: PMC3929414.

Kumar R, DiMenna L, Schrode N, Liu TC, Franck P, Muñoz-Descalzo S, Hadjantonakis AK, Zarrin AA, Chaudhuri J, Elemento O, Evans T. (2013) AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes. Nature 500(7460):89-92. doi: 10.1038/nature12299. Epub 2013 Jun 26. PubMed PMID: 23803762; PubMed Central PMCID: PMC3762466.

Faunes F, Hayward P, Descalzo SM, Chatterjee SS, Balayo T, Trott J, Christoforou A, Ferrer-Vaquer A, Hadjantonakis AK, Dasgupta R, Arias AM. (2013) A membrane-associated β-catenin/Oct4 complex correlates with ground-state pluripotency in mouse embryonic stem cells. Development 140(6):1171-83. doi: 10.1242/dev.085654. PubMed PMID: 23444350; PubMed Central PMCID: PMC3585656.

Kang M, Xenopoulos P, Muñoz-Descalzo S, Lou X, Hadjantonakis AK. (2013) Live imaging, identifying, and tracking single cells in complex populations in vivo and ex vivo. Methods Mol Biol 1052:109-23. doi: 10.1007/7651_2013_19. PubMed PMID: 23640250; PubMed Central PMCID: PMC3967584.